Memory complaints linked to higher risk of MCI & dementia

Data from 6257 older adults (aged 55-90) evaluated from 2005-2012 has revealed that concerns about memory should be taken seriously, with subjective complaints associated with a doubled risk of developing mild cognitive impairment or dementia, and subjective complaints supported by a loved one being associated with a fourfold risk. Complaints by a loved one alone were also associated with a doubled risk. Among those with MCI, subjective complaints supported by a loved one were associated with a threefold risk of converting to dementia.

Of the 4414 initially cognitively normal, 14% developed MCI or dementia over the course of the study (around 5 years); of the 1843 with MCI, 41% progressed to dementia.

http://www.futurity.org/worry-about-memory-predicts-alzheimer%E2%80%99s-risk/

[3573] Gifford, K. A., Liu D., Lu Z., Tripodis Y., Cantwell N. G., Palmisano J., et al.
(2014). The source of cognitive complaints predicts diagnostic conversion differentially among nondemented older adults.
Alzheimer's & Dementia. 10(3), 319 - 327.

seniors

Related News

Alzheimer's memory problems originate with oligomers not plaques

While everyone agrees that amyloid-beta protein is part of the problem, not everyone agrees that amyloid plaques are the cause (or one of them) of Alzheimer’s. Other forms of amyloid-beta have been pointed to, including floating clumps called oligomers or ADDLs.

More evidence for benefits of Rapamycin

A few months ago, I reported on an exciting finding that

New guideline on when people with Alzheimer's disease should stop driving

The American Academy of Neurology has updated its guidelines on when people with dementia should stop driving.

New gene associated with increased risk of Alzheimer's

Another gene has been identified that appears to increase risk of Alzheimer’s. The gene, MTHFD1L, is located on chromosome six.

Losing muscle mass early sign of Alzheimer’s

Previous research has found that unexplained weight loss is an early sign of Alzheimer's.

Memory problems not the only predictor of later mild cognitive impairment

Amnestic mild cognitive impairment often leads to Alzheimer's disease, but what predicts aMCI?

Apple juice improves behavior in Alzheimer's patients

A pilot study involving 21 institutionalized individuals with moderate-to-severe Alzheimer’s found that, although drinking two 4-oz glasses of apple juice daily for a month produced no change in the Dementia Rating Scale or in the Activities of Daily Living measure, there was a significant (27%)

TMS improves language comprehension in Alzheimer's sufferers

A pilot study involving 10 patients with moderate Alzheimer's disease, of whom half were randomly assigned to the treatment, has found that two weeks of receiving daily (25 minute) periods of repetitive transcranial magnetic stimulation to the prefrontal

Common Alzheimer's medication helps skills necessary for safe driving

A study involving outpatients with early stage Alzheimer’s found that their performance on some computerized tests of executive function and visual attention, including a simulated driving task, improved significantly after three months of taking

Cognitive ability, not age, predicts risky decisions

A study involving 54 older adults (66-76) and 58 younger adults (18-35) challenges the idea that age itself causes people to become more risk-averse and to make poorer decisions.

Pages