A new discovery helps explain why the “Alzheimer’s gene” ApoE4 is such a risk factor. It appears that ApoE4 causes a dramatic reduction in SirT1, an "anti-aging protein" that is targeted by resveratrol (present in red wine).
Resveratrol — an ingredient in red wine that has been implicated in a number of health benefits — has been found to inhibit interleukin 6 (IL-6), a pro-inflammatory protein that is part of the immune system (although IL-6 can be anti-inflammatory during exercise).
An Italian study has found that older adults with the highest concentration of resveratrol metabolites were no less likely to have died of any cause than those with no resveratrol found in their urine.
